"What we have found is the first evidence that bacteria can use sensed cues from their environment to infer future events," says Saeed Tavazoie, an associate professor in the department of Molecular Biology, who conducted the study along with graduate student Ilias Tagkopoulos and post-doctoral researcher Yir-Chung Liu. The research team, which included biologists and engineers, used lab experiments to demonstrate this phenomenon in common bacteria. They also turned to computer simulations to explain how a microbe species' internal network of genes and proteins could evolve over time to produce such complex behavior.
"The two lines of investigation came together nicely to show how simple biochemical networks can perform sophisticated computational tasks," says Tavazoie.
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